protein (OATP), multidrug-resistance associated protein (MRP)), a process sometimes


referred to as Phase III biotransformation (Figure 1-1).


MRP
OA TP


' OH


MRP
OA TP


'"r
 oHOH


I I


 \ cytosol ER membrane ER lumen
Figure 1-1. Schematic of select xenobiotic (represented by hydroxynaphthalene)
 biotransformation pathways in the mammalian cell. For abbreviations see text.


I