Abstract of Thesis Presented to the Graduate School of the University of Florida in Partial Fulfillment of the Requirements for the Degree of Master of Arts EFFECTS OF BOLUS CONSISTENCY ON TIMING AND SAFETY OF SWALLOW IN PARKINSON' S DISEASE By Michelle S. Troche May 2006 Chair: Christine Sapienza Major Department: Communication Sciences and Disorders Safety and timing of swallow are essential for health and quality of life. The study of swallow in Parkinson's disease (PD) is especially important, in that aspiration pneumonia is the leading cause of death in this population. One of the therapeutic strategies employed in the treatment of swallowing problems is diet modification. The primary aim of this study was to investigate the effects of bolus consistency on P-A score and timing of the oral-pharyngeal swallow of persons with PD. The secondary goal was to explore the relationship between various quantifiable components of hyoid movement and measures of swallow timing and penetration/aspiration. The videoradiographic images of ten participants with PD swallowing six thin, and six pudding thick boluses were measured. The results demonstrated various significant differences and relationships among the dependent variables (i.e., oral transit time, pharyngeal transit time, number of tongue pumps, P-A score, and SWAL-QOL measures). The implications for further research and clinical practice are discussed.