~L~ 11
~3

 EOL1


PDELSEED


E P-sandwich


Figure 1-3. Structure of the a subunit of E coli F1Fo ATP synthase. The residue numbers
 and subunit labels are color coded to match the subunits it represents. The E
 subunit has been suggested to undergo large conformational changes during
 catalysis from an overwhelming amount of biochemical data. Two different
 structures have been obtained for the a subunit, confirming the previous data.
 A) Superimposition of the Ca trace of the E structure obtained from isolated a
 subunit (u-helices shown in red and the P-sandwich shown in blue) with the
 structure obtained from the y-s complex (yellow). B) Composite structural
 model. Rotor stalk is based on the crystal structure obtained from the
 y-s complex. The PDELSEED, Ecu2 and the s P-sandwich are indicated to show
 the close proximity of PDELSEED and Su2 aS well as the relative distance
 between the Su2z and the s P-sandwich.


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