mL de-ionized water), 0.6 mL de-ionized water and 0.2 mL (0.1 M) phosphate buffer.

The solutions were shaken and incubated for approximately 100 hours. The resulting

solutions were filtered on a Kontes apparatus using a 0.45 micron Teflon filter. The

resultant film and residue were dried in a vacuum oven at 50 C until a constant weight

was reached. Each film was visually inspected for evidence of degradation. The 1HNMR

of the rotary evaporated filtrates revealed no degradation by products only phosphate

buffer.

Enzymatic Degradation of Isoleucinol Polymer (17)

 A 6.5 mg film was placed in buffered aqueous solution (1.0 mL, 0.02 M). A 7.1

mg film placed in the pH 11.0 aqueous solution (1.0 mL). A 7.7 mg film was placed in a

solution containing 70,000 units of the lipase from Rhizopus Arrhizus (dissolved in 0.2

mL de-ionized water), 0.6 mL de-ionized water and 0.2 mL (0.1 M) phosphate buffer.

An 11.7 mg film was placed in a solution containing 11,000 units of a-chymotrypsin

(dissolved in 0.2 mL de-ionized water), 0.6 mL de-ionized water and 0.2 mL (0.1 M)

phosphate buffer. A 5.5 mg film was placed in a solution containing 235,000 units of

Trypsin (dissolved in 0.2 mL de-ionized water), 0.6 mL de-ionized water and 0.2 mL

(0.1 M) phosphate buffer. A 4.6 mg film was placed in a solution containing 500 units of

papain (dissolved in 0.2 mL de-ionized water), 0.6 mL de-ionized water and 0.2 mL (0.1

M) phosphate buffer. The solutions were shaken and incubated for approximately 100

hours. The resulting solutions were filtered on a Kontes apparatus using a 0.45 micron

Teflon filter. The resultant film and residue were dried in a vacuum oven at 50 C until a

constant weight was reached. Each film was visually inspected for evidence of