CHAPTER 5 DISCUSSION Assumptions, Limitations, and Future Work Joint Model Selection If the current model cannot adequately reproduce future experimental motions, the chosen joint models may be modified. For example, the flexion-extension of the knee is not truly represented by a fixed pin joint (Churchill et al., 1998). When comparing the fitness of the optimum knee joint model to multi-cycle experimental marker data, the agreement was quite good for all knee flexion angles with the exception of those approaching full extension. By eliminating knee flexion angles less than 200, which comprised 18% of the flexion-extension data, the mean marker distance error was reduced to 0.48 + 0.23 cm (11.89% decrease) using the optimum model parameters from the full data set. A pin joint knee may be sufficiently accurate for many modeling applications. A 2 DOF knee model (Hollister et al., 1993) may account for the screw-home motion of the knee joint occurring between 00 and 200 (Blankevoort et al., 1988). If greater fidelity to actual bone motion is necessary, a 6 DOF knee joint may be implemented with kinematics determined from fluoroscopy (Rahman et al., 2003). Design Variable Constraints Certain joint parameters must be constrained to zero with the purpose of preventing the unnecessary optimization of redundant parameters. Case in point, the medial-lateral translational model parameter placing the knee joint center in the femur segment must be constrained to zero. On the other hand, this model parameter may be used as a design