25. Gross TS, McLeod KJ, Rubin CT. Characterizing bone strain distributions in vivo using three triple rosette stain gages. J of Biomechanics; 1992; 25(9): 1081-1087. 26. Gustafson MB, Martin RB, Gibson V, Storms DH, Gibeling J, Griffin L. Calcium buffering is required to maintain bone stiffness in saline solution. J of Biomechanics; 1996; 29(9): 1191-1194. 27. Huang J, Venkataraman S, Rapoff AJ, Haftka RT. Optimization of axisymmetric elastic modulus distributions around a hole for increase strength. Structural and Multidisciplinary Optimization 2002; accepted for publication. 28. Jepsen KJ, Davy, DT. Comparison of damage accumulation measures in human cortical bone. J of Biomechanics; 1997; 30: 891-899. 29. Jepsen KJ, Davy DT, Krzypow DJ. The role of the lamellar interface during torsional yielding of human cortical bone. J of Biomechanics; 1999; 32: 303-3 10. 30. Lee TC, O'Brien JO, Taylor D. The nature of fatigue damage in bone. International Journal of Fatigue; 2000; 22: 847-853. 31. Les CM, Stover SM, Keyak JH, Taylor KT, Willist NH. The distribution of material properties in the equine third metacarpal bone serves to enhance sagittal bending. J of Biomechanics; 1997; 30: 355-361. 32. Martin RB, Burr DB, Sharkey NA. Skeletal Tissue Mechanics. New York, SpringerVerlag, 1998. 33. Martin RB, Gibson VA, Stover SM, Gibeling JC, Griffin LV. Osteonal structure in the equine third metacarpus. Bone; 1996; 19 (2): 165-171. 34. Martin RB, Gibson VA, Stover SM, Gibeling JC, Griffin LV. Residual strength of equine bone is not reduced by intense fatigue loading: implications for stress facture. J of Biomechanics; 1997; 30:109-114. 35. Martin RB, Stover SM, Gibson VA, Gibeling JC, Griffin LV. In vitro fatigue behavior of the equine third metacarpus: remodeling and microcrack damage analysis. Journal of Orthopaedic Research; 1996; 14: 798-801. 36. McDonald DE, Palmer RH, Hulse DA, Neigut JS, Hyman WA, Slater MR. Holding power of threaded external skeletal fixation pins in the near and far cortices of cadaveric canine tibiae. Veterinary Surgery; 1994; 23:448-493. 37. Norwood GL. The bucked-shin complex in thoroughbreds. Proceedings of the American Association of Equine Practitioners; 1978; 24:319-36. 38. Nunamaker DM, Butterweck DM, Provost MT. Fatigue fractures in thoroughbred racehorse: relationships with age, peak bone strain and training. Journal of Orthopaedic Research; 1989; 8: 604-611.