TABLE OF CONTENTS
                                                                           pM. e

A CKN OW  LED GM  EN TS                                                      . iv

LIST OF  TABLES                                                             . vii

LIST OF  FIGURE  S                                                         . viii

A B S T R A C T                                                               . x

CHAPTER

I IN TRODU  CTION                                                             . 1

2 M ETH  OD S AN D M A TERIALS . 2

  A n a to m y                                                                . 2 Loading  Environm ent and Fracture Incidence . 3
  Bone Procurem ent and Identification                                        . 5
  B e am D im en sio n s                                                      . 5 M  achining of Beam s . 7
  D rillin g H o le s                                                         . 8 M  echanical Testing Setup . I I
  M echanical Testing Plan . 13
          M o n o to n ic T e sts                                            . 17 F         atig u e T e sts                                                  . 1 7
  S ta in in g                                                               . 1 8
  Sectioning of Beam s for M icroscopy                                       . 18
  M icroscopy Section Analyses Setup . 20
  M orphom etric Param eters . 21
  D am age Param eters . 23
  Specific Exam ples of D am age Types and Quantification                    . 24
  S tatistic al A n aly se s                                                 . 3 2

3 R E S U L T S                                                              . 3 5

  M orphom etric Param eters . 38
  D am age Param eters . 39

4 D IS C U S S IO N                                                          . 5 1



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