modeling [6, 7] for 1-dimensional signals such as respiratory ones, or 3 to 4-dimensional signals such as MR images [8]. 1.2 Of the Importance of Parameter Settings The complexity in using the gated experts approach stems from the number of parameters that have to be set specifically for the particular data before the system can work, and the potentially negative impact that one parameter change can have. Key parameters can be divided in two groups: the global system parameters such as performance measure and memory, which account for the accuracy in segmentation and adaptation of the experts (most of which will be addressed in chapter 2), and the local experts parameters, such as the kind of experts (linear vs. non-linear) or the type of basis for non-linear experts (global or local), which determine the prediction by the experts (they will be addressed in chapter 3). 1.3 Outline This thesis is comprised of six chapters. Chapter 2 presents more in-depth definitions concerning time series, stationarity, and the segmentation methods; chapter 3 focuses on describing data sets and problems of stationarity that entail generating a synthetic test set, then presents the different models used for modeling the data. Chapter 4 covers the results of segmentation by the different methods on the test set. In chapter 5 real data is used, and the results are reviewed and compared. Finally, chapter 6 summarizes the results of the simulations analysis and conclusions, and then opens doors for future work.