Hypotheses and methodological issues As Crisp (1970) pointed out, studies that investigated premorbid, or precancerous, personality factors leaned heavily upon theory and speculation which was far beyond what was immediately suggested by the data. The early studies tended to search for specific personality types associated with specific cancer types. As one group of reviewers (Surawicz, Brightwell, Weitzel, & Othmer, 1976) pointed out, personality was frequently defined in terms of psychodynamic variables. Despite the great variety of hypotheses advanced, according to Wellisch and Yager (1983) "no good hypotheses exist that specify which personality factors might lead to cancer for what specific reasons" (p. 145). In their thorough analysis of this literature, they asserted that "the best that those dealing in psychodynamics have been able to do thus far is to offer interpretations as to why people who already developed cancer have done so, but not why they rather than others have the disease" (p. 146). Early studies in this area are also characterized by serious methodological problems. As Surawicz et al. (1976) pointed out, the dif- ficulties with the approaches taken resulted in part from the lack of carefully designed longitudinal studies. As recognized in this review (1976), most studies did not have control groups but were based on clinical obser- vation of small numbers of cancer patients; the