psychosocial variables and the progression of cancer by identifying and controlling the variability in survival that was due to biological, disease, and medical variables. The focus was on the refinement of the procedure developed by Weisman and Worden (1975) through improvements in the measurement and evaluation of medical and disease variables. Research Questions The four research questions were stated as follows: 1. What psychosocial variables are positively correlated with survival? 2. What psychosocial variables are negatively correlated with survival? 3. What proportion of the variability in survival can be explained by a set of psychosocial variables? 4. What proportion of the variability in survival can be explained by a set of psychosocial variables and co-morbidity? Definition of Terms The definitions given in this section are presented in a sequence that reflects the relationships between the concepts. The terms defined include those having to do with cancer, cancer treatment, and with the variables studied in this research.