and the long journey toward a scientific understanding of the physiological nature of pain had begun. Modern approaches to the nature of the pain experience come from many disciplines. The gate theory proposed by Melzack and Dennis (1978) is perhaps the best known and most popular of the physiological approaches. Gate control theorists only attempt to explain the activity of the nervous system when pain is experienced. Gate control theory proposes that "neural mechanisms in the dorsal horns of the spinal cord act like a gate that can increase or decrease the flow of nerve impulses from peripheral fibers to the spinal cord cells that project to the brain" (Melzak & Dennis, 1978, p. 2). This adjustment of the nerve impulses takes place before injury or somatic input invokes pain perception and response. According to the theory, large fiber inputs close the gate, and small fiber inputs open the gate. The mechanism for the inhibition and facilitation is unknown. Since it is now known that all dorsal horn cells are under the control of fibers that descend from the brain, it is believed that descending influences such as motiva- tional drive and cognitive evaluative activities will also affect the gate. When the output of the spinal cord transmission exceeds a critical level, the individual experiences pain. "The complex sequences of behavior that characterize pain are determined by sensory, motiva- tional, and cognitive processes that act on motor mechanisms" (p. 12). Motor mechanisms are "all of the brain areas that contribute to overt behavioral response patterns" (Melzak & Dennis, 1978, p. 12). The affective influence espoused by the ancients seems consistent with current research of scientists such as Melzack and Dennis.