FIELDS OF INSTRUCTION 192 instructor. Current understanding of molecular basis of cancer. Offered in odd-numbered years. GMS 6065: Fundamentals of Cancer Biology (2) Prereq: GMS 6001 or consent of instructor. Broad-based introduction into causes of cancer, molecular and biological processes involved in malignancies, and current cancer treatment approaches. GMS 6331: Stem Cell Biology (1) Prereq: GMS 6001 or consent of instructor. Recent progress in mammalian stem cell research. GMS 6635: Organization of Cells and Tissues (2) Prereq: GMS 6001 or consent of instructor. Structural and functional aspects. GMS 6642: Morphogenesis: Organ Systems I (2) Prereq: GMS 6635, second-year IDP student. Skin, respiratory, lymphatics, and special sense. GMS 6643: Morphogenesis: Organ Systems II (2) Prereq: GMS 6642, second-year IDP student. GI, kidney, endocrine, male and female reproduction. GMS 6644: Apoptosis (1) Prereq: GMS 6001 or consent of instructor. Modern view of molecular mechanisms of tumor development. Offered in even-numbered years. GMS 6690: Molecular Cell Biology Journal Club (1; max: 12) Faculty-student discussion of research papers and topics. Advanced Concentration in Neuroscience Graduate Faculty 2006-2007 Director: S. Semple-Rowland. Eminent Scholars: D. K. Anderson; P. Hargrave. Distinguished Professors: B. W. Ache; S. A. Benner; M. Gold. Professors: P. A. V. Anderson; B. Battelle; S. Blackband; B. Cooper; P. Davenport; W. Dawson; D. Driscoll; W. H. Drummond; W. A. Friedman; R. L. Hayes; M. B. Heaton; M. W. Heft; P. M. Hoffman; R. D. Johnson; H. Jones; P. S. Kalra; S. P. Kalra; M. Keller- Wood; W. Kem; C. M. Leonard (Emerita); M. H. Lewis; P. Linser; W. G. Luttge (Emeritus); R. J. Mandel; D. F. Muir; J. B. Munson (Emeritus); H. Nick; J. M. Petitto; D. Price; M. Raizada; R. L. Reep; S. Roper; J. C. Sackellares; N. Scarpace; P. J. Scarpace; P. G. Shaw; P. Small; P. W. Stacpoole; D. Steindler; W. J. Streit; C. Sumners; F. J. Thompson; T. W. Vickroy; C. J. Vierck (Emeritus); D. W. Walker (Emeritus); C. E. Wood; R. Yezierski. Associate Professors: K. J. Anderson; D. Bloom; D. Bolser; D. R. Borchelt; R. Caudle; B. Y. Cooper; A. Edison; T. Foster; J. K. Harrison; C. Haskell-Luevano; L. F. Hayward; M. A. King; J. A. Klein; A. Mauderli; L. L. Moroz; R. L. Papke; J. Petitto; L. A. Ritz; S. L. Semple-Rowland; K. Wang; I. D. Weiner; R. T. Zori. Assistant Professors: P. K. Bose; P. Carney; C. Frazier; D. R. Howland; Y. Liu; J. Long; A. Martynyuk; J. K. Neubert; F. Ono; A. K. Ottens; W. C. Smith; S. Svetlov; S. L. Xia; D. A. Zacharias. The Graduate Faculty associated with the neuroscience advanced concentration have expertise in neuroanatomy, molecular and cellular neurobiology, neurodevelopment and aging, neurotransmitter chemistry and pharmacology, neuro- endocrinology and immunology, cellular and molecular neuro- oncology, cellular and membrane neurophysiology, somatosen- sory and motor systems, transplantation neurobiology, injury and repair of the CNS, and neurobehavioral sciences. Study in marine vertebrate and invertebrate neurobiology is available through Graduate Faculty at the Whitney Laboratory. GMS 6021: Principles of Neuroscience I: Development and Plasticity of Central Nervous System(l) Prereq: GMS 6001 or consent of instructor. Principles governing neural development and plasticity of the vertebrate central nervous system. GMS 6022: Principles of Neuroscience II: Signaling in Nervous System (1) Prereq: GMS 6001 or consent of instructor. Principles governing intercellular communication within the nervous system. GMS 6023: Principles of Neuroscience III: Neural Integration and Control (1) Prereq: GMS 6001 or consent of instructor. Principles governing the integration and control of information processing within the central nervous system. GMS 6029: Brain Journal Club (1; max: 12) Prereq: Consent of instructor. Offers students opportunities to present and participate in discussions of top-tier research papers in the neu- rosciences. S/U. GMS 6051: Signal Transduction (1) Prereq: GMS 6001 or consent of instructor. Focused on the mechanisms underlying cellular signal transduction. GMS 6052: Ion Channels of Excitable Membranes (1) Prereq: Consent of instructor. Cell's membrane potential represents important source of energy used to regulate intracellular ion con- centration, to control secretary process, and as basis for electrical signaling in nervous system. Background understanding of ion channel proteins that regulate and respond to cell membrane potential. GMS 6072: Neuroendocrinology and Neuroimmunology (1) Prereq: GMS 6007 or consent of instructor. Cellular and molecular mechanisms regulating interactions between the immune, endocrine, and nervous systems. GMS 6073: Developmental Neurobiology (1) Prereq: GMS 6007 or consent of instructor. Focuses on current research that is being conducted to build upon an understanding of how the nervous system develops. Both cellular and molecular perspec- tives will be examined. GMS 6074: Comparative Neurobiology (2) Prereq: GMS 6007 or consent of instructor. Provides a broad perspective on nervous system evolution, structure and function in different species. Comparisons of the cytoarchitectural principles that produce mammalian nervous systems will be an additional focus. GMS 6078: Synaptic Function and Plasticity (1) Prereq: Consent of instructor. Synapses that mediate fast electrical excitation and inhibition in mammalian brain and how these synapses change with development and experience. Lectures will cover the molecular biology of glutamate, GABA, and nicotinic acetylcholine receptor subtypes, experimental paradigms for studying long lasting changes in synaptic function, and changes in animal behavior in relation to neuroplastic events. GMS 6079: Computers in Biology (1) Prereq: GMS 6001 or consent of instructor. Students will be introduced to the use of computers in studies of protein and nucleic acid sequences and cellular function. GMS 6080: Basic Magnetic Resonance Imaging (1) Prereq: GMS 6007 or consent of instructor. Principles behind nuclear magnetic resonance imaging (MRI) and spectroscopy (MRS) and how these methods are applied to studies of the human brain. GMS 6592: Ion Channels Journal Club: Pharmacology, Biophysics, and Neuroscience of Excitable Membranes (1) Discussions of recent papers in the context of larger issues in therapeutics and neuroscience led by students and faculty. S/U. GMS 6705: Functional Human Neuroanatomy (4) Prereq: Consent of instructor. Intensive introduction to the anatomy, function, and dysfunction of the human central nervous system. GMS 6709: Current Topics in Vision (1) Prereq: GMS 6001 or