STATISTICS / 291

problems of estimation and tests of hypotheses; distribution theory under normal
assumptions.
STA 620-THEORY OF COMPLETELY RANDOM AND MIXED MODELS. 4 credits
 Prerequisite: STA 619. General theory and application of completely random
and mixed models. Reference to problems in estimation and tests of hypotheses.
STA 621-DESIGN OF EXPERIMENTS. 4 credits
 Prerequisite: STA 609. Continuation of STA 609. Applications of confounding
and fractional replication, design and analysis of balanced and partially balanced
incomplete block designs, further considerations of the mixed model.
STA 622-SAMPLING THEORY AND APPLICATION. 4 credits
 Prerequisite: STA 611. Theory of basic sampling procedures in economic and
social surveys. Multistage sampling, cost functions, double sampling, sampling of
time series.
STA 623-THE ANALYSIS OF MULTIVARIATE DATA. 4 credits
 Prerequisite: STA 604 or STA 609. Multivariate normal distribution; dis-
 criminant; canonical, principal component; and factor analysis.
 STA 624-SAMPLING THEORY AND APPLICATION 2. 4 credits
 Prerequisite: STA 622. Continuation of STA 622. Stochastic processes as ap-
 plied to sampling theory and other current research topics in sampling.
 STA 626-APPLIED TIME SERIES ANALYSIS. 4 credits
 Prerequisite: STA 442 or STA 607. Linear time series models; statistical
 analysis of linear stationary and nonstationary time series, with application and
 case studies supplemented by simulation studies.
 STA 628-PROBLEMS IN STATISTICS. 1 to 5 credits
 Prerequisite: Permission of department. Special problems in research methods,
 sampling methods, and experimental design. May be repeated with change of
 content up to a maximum of 9 credits.
 STA 630-INDIVIDUAL WORK. 1 to 5 credits
 Prerequisite: Permission of department. Special topics designed to meet the
 needs and interests of individual students. May be repeated with change of
 content up to a maximum of 15 credits.
 STA 635-BIOSTATISTICS 1. 4 credits
 Prerequisite: STA 604 or STA 609. Statistical methods in biological assay;
 direct assays; indirect assays; dose-response relationships; nonlinear regression;
 parallel line assays; potency estimation.
 STA 636-BIOSTATISTICS 2. 4 credits
 Prerequisite: STA 635. Inferences from hospital data; nonparametric methods
 in medical research including distribution free multiple comparisons, rank analysis
 of covariance, indices of order association; nonparametric partial correlation;
 multidimensional contingency tables.
 STA 637-BIOSTATISTICS 3. 4 credits
 Prerequisite: STA 636. Multivariate problems in biostatistics; repeated measure-
 ments; discriminant analysis; diagnostic models; factor analysis; current topics in
 biostatistics.
 STA 640-PROBABILITY THEORY 1. 4 credits
 Prerequisites: STA 610, advanced calculus. Measure theoretic approach to
 probability: random variables, probability functions, distribution functions, ex-
 pectation, characteristic functions.
 STA 641-PROBABILITY THEORY 2. 4 credits