216 / FIELDS OF INSTRUCTION ME 686-SPATIAL KINEMATIC SYNTHESIS AND ANALYSIS. 3 credits Geometry of motion in three dimensions. Single position design depending on orders of contact with spatial curves. Finitely separated position design by matrix methods. Synthesis and analysis of spatial motions. ME 687-COMPUTER-AIDED DESIGN: OPTIMIZATION. 3 credits Prerequisites: ISE 470, ME 579. Parameter optimization techniques in machine systems. ME 689-SIMILITUDE IN MECHANICAL ENGINEERING DESIGN. 3 credits Principles of similitude for model design, analysis, and design analogies. Similitude as a basis for design optimization. ME 690-MECHANICAL RESEARCH 1. 1 to 3 credits Research projects in mechanical engineering. May be repeated with change of content up to a maximum of 6 credits. ME 691-MECHANICAL RESEARCH 2. 1 to 3 credits Prerequisite: ME 690. Continuation of ME 690. May be repeated with change of content up to a maximum of 6 credits. ME 692-ADVANCED MECHANICAL LABORATORY 1. 3 credits Experimental projects in mechanical engineering. ME 693-ADVANCED MECHANICAL LABORATORY 2. 3 credits Continuation of ME 692. ME 695-GRADUATE SEMINAR. 1 credit May be repeated with change of content up to a maximum of 9 credits. Graded on an S/U basis. ME 697-SUPERVISED RESEARCH. 1 to 5 credits Credit not applicable toward degree. May be repeated. ME 698-SUPERVISED TEACHING. 1 to 5 credits Credit not applicable toward degree. May be repeated. ME 699-MASTER'S RESEARCH. 1 to 17 credits ME 799-DOCTORAL RESEARCH. 1 to 17 credits MEDICAL SCIENCES-GENERAL (College of Medicine) Programs leading to the Doctor of Philosophy degree in the basic medical sciences with a major in immunology and medical microbiology, neuro- science, pathology, pharmacology, and physiology are offered by the College of Medicine. In addition, a program in radiation biophysics leading to a Master of Science degree is available. Training in these scientific disciplines is planned to prepare the student for a career in research and teaching, rather than in clinical practice, for which the Doctor of Medicine degree program is designed. A minor is not required but may be chosen in another of the basic sciences listed below or elsewhere in the Catalog. All facilities of the College of Medicine are available to graduate students in this program. Though an undergraduate major in biological or physical science is desirable, concentration in mathematics or engineering is an appropriate foundation for the Doctor of Philosophy degree in medical sciences. Satisfactory com-