194 / FIELDS OF INSTRUCTION elements of microorganisms and mechanics of their regulatory systems. Mechanisms of control of microbial DNA replication, cell division, ribosome and cell-wall formation; kinetic studies of normal and abnormal growth. MED 659-PRINCIPLES OF IMMUNOLOGY. 5 credits Identical with MCY 659. Prerequisite: MCY 505 or MED 551. Biological and biochemical aspects of host resistance and immunity; the chemical and physico- chemical properties of the proteins of immune reactions. MED 660-IMMUNOLOGY LABORATORY. 3 credits Identical with MCY 660. Corequisite: MED 659. Consent of staff required. MED 661-BIOLOGY OF UNCOMMON MICROORGANISMS. 5 credits Identical with MCY 661. Prerequisite: MCY 302. Natural distribution, meta- bolic activities, isolation, and culture of selected groups of microorganisms. MED 662-MICROBIAL GENETICS. 5 credits Identical with MCY 662. Prerequisite: MCY 521, general genetics. Microbial genetics, including mutation, selection, transformation, transduction, conjugation, and episomal factors; molecular structure and function of genes. MED 663-PARASITIC DISEASES OF THE TROPICS AND SUBTROPICS. 5 credits Identical with MCY 663, VY 663, ZY 663. See MCY 663. MED 664-VIRAL DISEASES. 3 credits Identical with MCY 664. Prerequisite: MED (MCY) 652. Pathogenesis of viral disease including cytopathic and oncogenic viruses. Diagnostic and preventive measures. MED 665-MICROBIAL INFECTIONS. 5 credits Pathogenesis of selected bacterial and fungal diseases, emphasizing the clinical and pathological aspects of human infection. MED 666-MICROBIOLOGY 1. 6 credits Identical with MCY 666. Intensive review of principles of immunity, physiology, and genetics of bacteria, virology, infection, and ecology. (See also MED 667.) MED 667-MICROBIOLOGY 2. 3 credits Identical with MCY 667. Continuation of MED 666. MED 668-REGULATION IN BIOLOGICAL SYSTEMS. 5 credits Identical with MCY 668. Prerequisites: MCY 520, MCY 521, MCY 657; BCH 601, BCH 602. Control of enzyme activity: kinetic, structural, inhibition (allosteric and non-allosteric), and energy level control; permeases; control of enzyme synthesis: positive and negative; repression, induction, catabolic repression, cyclic AMP; hormonal control. MED 669-SEMINAR. 1 credit Identical with MCY 669. Attendance required of all graduate majors at one research presentation and one graduate report each week as scheduled. May be repeated with change of content. MED 750-JOURNAL COLLOQUY. 1 credit Identical with MCY 750. Critical presentation and discussion of recent original articles in the microbiological literature. May be repeated with change of content MED 751-RESEARCH CONFERENCE. 1 credit Identical with MCY 751. Critical discussion and appraisal of research pro- grams of faculty and students of the department. May be repeated with change of content.