150 / FIELDS OF INSTRUCTION


Pharmacodynamics, and Pharmacy Health Care Admini-
stration must have an undergraduate degree in pharmacy,
chemistry, biology, or related sciences. Students who wish
to concentrate their study in hospital pharmacy administra-
tion must have either a Doctor of Pharmacy or Bachelor of
Science in Pharmacy degree and be a licensed pharmacist.
 Satisfactory completion of a thesis or dissertation based
on research is a requirement for a graduate degree in the
pharmaceutical sciences.
 Inquiries regarding applications and general information
about the graduate programs are processed through the
Office of the Dean, College of Pharmacy.

PHA 6905L-Research Methods in Pharmaceutical Sciences (1-
4; max: 12)
PHA 6910-Supervised Research (1-5; max: 5) S/U.
PHA 6935-Selected Topics in Pharmacy (2; max: 4) Open to all
departments in the College of Pharmacy.
PHA 6936-Advanced Topics in Pharmaceutical Sciences (1;
max: 4) Written and oral presentation of research designs, proto-
cols, papers, and critical appraisals with discussion and critical
review of such topics.
PHA 6938-Research Seminar (1; max: 3) Seminar required of
graduate students in the College of Pharmacy. S/U option.
PHA 6940-Supervised Teaching (1-5; max: 5) S/U.
PHA 6971-Research for Master's Thesis (1-15) S/U.
PHA 7979-Advanced Research (1-9) Research for doctoral
students before admission to candidacy. Designed for students
with a master's degree in the field of study or for students who have
been accepted for a doctoral program. Not open to students who
have been admitted to candidacy. S/U.
PHA 7980-Research for Doctoral Dissertation (1-15) S/U.



PHARMACEUTICS
College of Pharmacy

 GRADUATE FACULTY 1992-93
 Chairman: H. Derendorf. Graduate Coordinator: R. H.
 Hammer. Graduate Research Professor: N. Bodor. Profes-
 sors: R. H. Hammer; M.A. Schwartz. Associate Professors:
 H. Derendorf; G. Hockhaus; H. Schrier. AssistantProfessor:
 M. A. Longer.

 The Department of Pharmaceutics offers the Doctor of
 Philosophy and Master of Science in Pharmacy in the
 pharmaceutical sciences. Pharmaceutics is the scientific
 endeavor concerned with the design, formulation, evalu-
 ation, and use of drug delivery systems. A foundation in
 physical chemistry, chemistry, mathematics, as well as in
 the life sciences, is necessary. Its domain extends from
 studies of the physiochemical properties of drugs and
 related molecules to investigations of the mechanisms of
 physiological processes affecting drug delivery and thera-
 peutic effectiveness.
 The general focus of research in the Department involves
 the study of the design and evaluation of the dosage form.
 The design involves physical chemical studies and devel-
 opment of analytical techniques involving spectroscopy
 and chromatography. Evaluation includes the develop-
 ment of sensitive analytical techniques for the drug in
 biological fluids and the subsequent biopharmaceutical
 and clinical pharmacokinetic studies.

 PHA 5121--Clinical Pharmacokinetics (4) Integrating and apply-
 ing pharmacokinetic principles to formulate a rational dosage
 regimen considering various patient factors and drug product
 factors.
 PHA 5124-Biopharmaceutics (4) Time course of drugs in the


body with reference to their absorption, distribution, metabolism,
and elimination. Rate processes, the physiochemical influences
on absorption, distribution, metabolism, and elimination and
formulation factors involved in drug delivery and availability.
PHA 5126-Surface Chemistry of Biological Systems (2) Surface
chemistry of fluid interfaces and its application to biomembranes
and drug biomolecule interactions.
PHA 5161-Pharmaceutical Biotechnology (3) Principles of
recombinant DNA technology necessary to interact and commu-
nicate as a pharmaceutical scientist within biotechnology field.
Discussion of recombinant peptide and protein drugs, including
protein purification, stability, quality control, and dosage form
design.
PHA 6107C-Parenterals (3) Principles of preparation and ster-
ilization. Properties of materials, stability, and interactions.
PHA6115-Equilibria, Complexations, and Interactions of Drugs
(3) Models for drug interactions in solution. Physical chemistry
characteristics of drugs and their complexes in pharmaceutical
systems.
PHA 6116-Stability and Kinetics of Drugs (3) Kinetics, mecha-
nisms, and prediction of stability of in vitro transformations of
drugs in solution and in dosage forms.
PHA 6125-Pharmacokinetics and Biopharmaceutics (3) Com-
partmental analysis with computers.
PHA 6170C-Pharmaceutical Product Formulation (3) The ra-
tionale and design of pharmaceutical dosage forms.
PHA 6416-Pharmaceutical Analysis I (3) Theory and applica-
tions of separation of drugs and breakdown products from dosage
forms and biological media.
PHA 6417-Pharmaceutical Analysis 11 (3) Absorption, fluores-
cence, phosphorescence, and spectroanalysis of drugs and re-
lated compounds.




PHARMACODYNAMICS
College of Pharmacy

 GRADUATE FACULTY 1992-93
 Chairman: M. J. Katovich. Graduate Coordinator: M. J.
 Meldrum. Professors: K. F. Finger; M. J. Katovich; J. W.
 Simpkins. Associate Professors: R. Dawson; M. J. Meldrum;
 W. J. Millard; C. A. Sninsky. Assistant Professors:M. Keller-
 Wood; J. N. Peris.

 The Department of Pharmacodynamics offers the Doctor
 of Philosophy and Master of Science in Pharmacy in the
 pharmaceutical sciences with a specialization in
 pharmacodynamics. Pharmacodynamics is an integrated
 field of study involving pharmacology, physiology, and
 toxicology in a holistic approach to drug action in living
 systems. The Department focuses on neuroendocrinology,
 cardiovascular pharmacology, and neuropharmacology
 with diverse research interests in aging, hypertension,
 reproduction, menopause, neurotoxicity, and environmental
 physiology.
 An undergraduate degree in pharmacy, chemistry, biol-
 ogy or related sciences is required. In addition to graduate
 courses in pharmacy, courses are taken in pharmacology
 and biochemistry in the College of Medicine and in statis-
 tics in the College of Liberal Arts and Sciences.

 GMS 5403-Advanced Endocrinology (4) Prereq: GMS 5400C,
 PHA 3500, 3501 or equivalent, consent of instructor. Readings
 discussions, and lectures on recent advanced in endocrinology.
 PHA 5531-Neurotoxicology (2) Prereq: biochemistry, physiol-
 ogy, and consent of instructor. Survey of major classes of agents
 known to cause toxic effects in central and peripheral nervous