BOTANY/73 Cain; P. M. McGuire; T. Yang. Assistant Scientists: N. D. Denslow; M. J. Koroly. The Departmentof Biochemistry and Molecular Biology offers the Master of Science and Doctor of Philosophy degrees in biochemistry with specialization in physical biochemistry, molecularbiology, cell biology, and medical biochemistry. Specific areas of study include structure and function of cellular and nuclear membranes in mammalian cells;trans- port of molecules into the cell; regulation of cell division and gene expression; X-chromosome inactivation; assem- bly and regulation of the cytoskeleton; biochemistry of differentiation; biochemical genetics; molecular biology of nucleic acids; site-directed mutagenesis; replication and repair in bacterial and eukaryotic cells; biosynthesis and structure of nucleic acids, proteins, polysaccharides, lipids, lipoproteins, sensory biochemistry; isoprenoid metabo- lism; physical biochemistry of nucleic acids and proteins; mechanism of enzyme action; and molecular evolution. New graduate students should have adequate training in general, organic, quantitative, and physical chemistry as well as in physics, biology, and calculus. Minor deficiencies may be made up immediately after entering graduate school. Doctoral candidates are required to take several bio- chemistry courses which include BCH 6156C, 6206,6415, 6740, 6876, and 6936. Depending upon interests and background of the student, additional courses are recom- mended from the following list: BCH 6296, 6746, 7410, and 7515. The curriculum for doctoral candidates may also include advanced chemistry, physiology, microbiology, and genetics courses. BCH 6156C-Research Methods in Biochemistry (1-4; max: 8) Coreq: BCH 6415, 6740. Only by special arrangement._Bio- chemical research in which the student refines research tech- niques in physical biochemistry, intermediary metabolism, mo- lecular biology, and cell biology under supervision of a staff member. BCH 6206-Advanced Metabolism (3) Prereq:generalbiochem- istry or consent of instructor. The reactions of intermediary metabolism with emphasis upon their integration, mechanisms, and control. One of the three core biochemistry courses. BCH 6296-Advanced Topics in Metabolic Control (1; max: 6) Prereq: BCH 6206, 6415, 6740, or consent of instructor. Study of the thermodynamic, allosteric, hormonal, and genetic control of metabolic reactions. BCH 6415-Advanced Molecular and Cell Biology (3) Prereq: general biochemistry or consent of instructor. An advanced course in the molecular biology of pro- and eukaryotes. Topics will include DNA replication, chromosome organization, RNA and protein synthesis, and molecular aspects of gene regulation. One of the three core biochemistry courses. BCH 6740-Advanced Physical Biochemistry (3) Prereq:general biochemistry and physical chemistry or consent of instructor. Physical chemistry of biological molecules and the techniques for their study. Constitutes one of the three core bioc chemistry courses. BCH 6746-Advanced Topics in Physical Biochemistry (1; max: 6) Prereq: BCH 6206, 6415, 6740, or consent of instructor. Study of physical chemistry of proteins, nucleic acids, lipids, enzymes, as well as their modes of interaction. BCH 6876-Recent Advances in Biochemistry (1) Prereq: BCH 6740 orequivalent. Areas of biochemistry and molecular biology, selected bythefaculty, discussed critically and in depth. Emphasis on current controversy and theory, data interpretations, and scientific writing. Classes held informally in small groups, during each semester, involving all biochemistry faculty on a rotating basis. S/U. BCH 6910-Supervised Research (1-5; max: 5) S/U. BCH 6936-Biochemistry Seminar (1; max: 20) Required of graduate students in biochemistry; open to others by special arrangement. Research reports and discussions of current re- search literature given by the departmental staff, invited speakers, and graduate students. BCH 6940-Supervised Teaching (1-5; max: 5) S/U. BCH 6971-Research for Master's Thesis (1-15) S/U. BCH 7410-Advanced Topics in Molecular Biology (1; max: 6) Prereq: BCH 6206, 6415, 6740, or consent of instructor. The biochemical basis of molecular biology and genetics with empha- sis on the mode of control surrounding the replication and expression of the pro- and eukaryotic genome. BCH 7515-Enzyme Kinetics and Mechanisms (2) Prereq: ad- vancedgeneral course in biochemistry such as BCH 6740, 6206, or consent of instructor. The study of enzyme reaction mecha- nisms using kinetics, spectroscopy, protein crystallography, and new emerging techniques. Alternates with BMS 6203, spring semester. BCH 7979-Advanced Research (1-9) Research for doctoral students before admission to candidacy. Designed for students with a master's degree in thefield of study orfor students who have been accepted for a doctoral program. Not open to students who have been admitted to candidacy. S/U. BCH 7980-Research for Doctoral Dissertation (1-15) S/U. BMS 6203-Cell Membranes: Molecular Biology and Function (2) Prereq: BCH 4024 andMCB 3020 or equivalents and consent of instructor. Composition, molecular organization, and assembly of biological membranes in both eukaryotes and prokaryotes. Alternates with BCH 7515, spring semester. GMS 5621-Cell and Tissue Biology (4) Prereq: cell biology course and consentof instructor. Cell specializations and interac- tions that account for the organization and functions of the basic tissues (epithelium, connective tissue, muscle, and nerve). BOTANY College of Liberal Arts and Sciences and Agriculture GRADUATE FACULTY 1992-93 Chairman: D. A. Jones. Graduate Coordinator:J. T. Mullins. Graduate Research Professors: D. Dilcher; I. K. Vasil. Professors: H. C. Aldrich; G. E. Bowes;J. S. Davis; J.J. Ewel; D. R. Gordon; D. G. Griffin, Ill;W. S.Judd;S. R. Manchester; J. T. Mullins; F. E. Putz; R. C. Smith;W. L. Stern; D. B. Ward; N. H. Williams. Associate Professor: T. W. Lucansky. Assistant Professors: A. C. Harmon; K. Williams. The Department of Botany offers graduate work leading to the degrees of Master of Science, Master of Agriculture, Master of Science in Teaching, and Doctor of Philosophy. The faculty encompass three general areas of expertise: biochemistry and physiology, ecology and population ge- netics, systematics and evolution. Specific areas of special- ization include anatomy/ morphology with emphasis on tropical ferns, aquatic and woody plants, and orchids; bryology; ecology and environmental studies; ecological, cellular, and molecular genetics; mycology with emphasis on physiology and development; algology with emphasis on algae of brine ponds; physiology and biochemistry with emphasis on ion uptake, photosynthesis and photorespira- tion, growth and development of selected fungi, calcium- binding proteins and protein phosphorylation; systematics with emphasis on monographic and floristic studies; paleo- botany; physiological ecology; tropical botany and ecol- ogy.