PHARMACY / 125


pursue courses in biochemistry, physiology, and other
medical sciences as determined by consultation with
their advisory committees.
BMS 5465-Advanced Medical Pharmacology (4)
BMS 6400-Introduction to Pharmacology (5) Prereq:
elementary courses in biochemistry and physiology. Over-
view of the entire field of pharmacology as the study of the
interactions between living systems and foreign chemicals.
Intended to prepare majors for advanced courses or to famil-
iarize nonmajors with the area.
BMS 6402-Autonomic and Cellular Pharmacology (2) Pre-
req: BMS 6400. A biochemical approach to the actions of
drugs on the autonomic nervous system, receptor coupling
mechanisms, modulation of neurotransmitter release, and
immune system pharmacology.
BMS 6403-Renal and Endocrine Pharmacology (2) Prereq:
BMS 6400. Pharmacology and toxicology of hormones and
renal drugs.
BMS 6420-Seminar in Pharmacology (1) Prereq: BMS 6400.
Research reports and discussions of current research liter-
ature by graduate students, faculty, and invited lecturers.
BMS 6463-Molecular Pharmacology (3) Prereq: BMS 6400,
CHM 3401. A biochemical approach to the actions of drugs,
stressing analysis of drug-receptor interactions, structure-ac-
tivity relationships, kinetics of distribution of drugs, and me-
tabolism of foreign compounds.
BMS 7421-Research Methods in Pharmacology (1-3; max: 6)
Readings, discussions, and practical experience with modern
methods used in pharmacology. Chemical and biological
methods.
BMS 7423-Topics in Pharmacology and Toxicology (1-3;
max: 12) Seminars, informal conferences, or laboratory work
on selected topics.
BMS 7467-Physiology and Pharmacology of Excitable
emembranes (2) Membrane ionic permeability changes un-
derlying action and synaptic potential generation described
in detail. Applications of electrophysiological and radio-
active tracer techniques to analysis of drug action on ex-
citable membranes.
GMS 6735-Neuropharmacology (3) Prereq: background in
biochemistry and basic neuroscience or consent of instruc-
tor. The identification, synthesis, metabolism, and pharma-
cology of neurotransmitters and their receptors, to include
biogenic amines, neuropeptides, and other nervous system
transmitters.


PHARMACY
College of Pharmacy
 GRADUATE FACULTY 1984-85
Chairman: M. A. Schwartz. Graduate Coordinator: R.
J. Bergeron. Graduate Research Professor: E. R.
Garrett. Professors: O. E. Araujo; S. J. Curry; K. F. Fin-
ger; L. S. Hendeles; J. H. Perrin; S. G. Schulman; M. A.
Schwartz; R. B. Stewart; F. A. Vilallonga. Associate Pro-
fessors: R. A. Angorn; P. L. Doering; F. P. Field; V. P.
Gotz; M. J. Katovich; C. L. Kimberlin; M. A. Lemberger;
W. C. McCormick; M. W. McKenZie; M. P. Pevonka; j.
D. Robinson; J. W. Simpkins; R. L. Yost. Assistant Pro-
fessors: D. Bradham; H. Derendorf; C: L. DeVane; L.
M. Lopez; C. Riley; K. Thakker; R. Williams.
 The College of Pharmacy offers the Dottor of Phi-
losophy and the Master of Science in Pharmacy de-
grees with a major in pharmaceutical sciences. The
approved areas of specialization within the major of
pharmaceutical sciences are medicinal chemistry and
pharmacy. The specialization of pharmacy allows stu-
dents to concentrate their study in the following
areas: pharmaceutics, pharmacodynamics, pharmacy
health care administration, and hospital pharmacy ad-
ministration.
 Students who wish to concentrate their study in the
 area of pharmacy health care administration must


have a baccalaureate degree but applicants do not
need an undergraduate degree in pharmacy. Students
who wish to concentrate their study in the area of
hospital pharmacy administration must have a
Bachelor of Science in Pharmacy and licensure as a
pharmacist, while an undergraduate degree in phar-
macy, chemistry, biology, or related sciences will be
accepted in the scientific areas.

HCA 5455-Quality Assurance in the Health System (2) Pre-
req: HCA 6101 or consent of instructor. Various factors relat-
irng to quality assurance issues are examined. Past and cur-
rent programs are critically reviewed, while developing the
guidelines, processes, etc., for initiating and maintaining
new approaches.
HCA 6117-Health Policy Analysis (3) Prereq: STA 6201, 6707
or equivalent and ECP'6536. Students apply research meth-
odologies which involve economic analysis to specific
health policy issues. Computerized data sets of social, eco-
nomic, and health services utilization characteristics are pro-
vided.
HCA 6425-Health Care Administration in Long Term Care
Settings (2) Prereq: HCA 6101 or consent of the instructor.
Disease and health care utilization trends of the elderly pop-
ulation are reviewed. The organizational structure of LTC fa-
cilities are examined. The regulation, reimbursement, and
quality assurance mechanisms used in LTC are analyzed.
PHA 5121-Clinical Pharmacokinetics (3) Prereq: PHA 4120
or by special arrangement. Integrating and applying pharma-
cokinetic principles to formulate a rational dosage regimen
considering various patient factors and drug product factors.
PHA 5126-Surface Chemistry of Biological Systems (2)
Study of surface chemistry of fluid interfaces and its applica-
tion to biomembranes and drug-biomolecule interactions.
PHA 5356-Cancer Chemotherapy (2) Prereq: PHA 4350 and
BCH 4203. Coreq: PHA 4436. The chemotherapeutic agents
which are currently in clinical use or under trial are classified
according to their general mode action and are presented
with their relevant chemical, pharmaceutical, and biological
characteristics.
PHA 5508-Principles of Endocrinology (3) Prereq: course in
physiology.
PHA 5601-Individualizing Dosage Regimens (3) Prereq: un-
dergraduate course in pharmacokinetics and biopharmaceu-
tics. Use of pharmacokinetic principles in the selection and
evaluation of drug therapy. The practical application of
pharmacokinetic techniques to the development of dosage
regimens is emphasized.
PHA 6107C-Parenterals (3) Principles of preparation and
sterilization. Properties of materials, stability and interac-
tions.
PHA 6115-Equilibria, Complexations, and Interactions of
Orugs (3) Prereq: CHM 4412; MAC 3314 or MAP 5304 or spe-
cial arrangement. Models for drug interactions in solution.
Physical chemistry characteristics of drugs and their com-
plexes in pharmaceutical systems.
PHA 6116-Stability and Kinetics of Drugs (3) Prereq: CHM
6440, and PHA 6115 or special arrangement. Kinetics, mecha-
nisms, and prediction of stability of in vitro transformations
of drugs in solution and in dosage forms.
PHA 6125-Pharmacokinetics and Biopharmaceutics (3) Pre-
req: PHA 6116 and a course in pharmacology, or by special
arrangement. Compartmental analysis with computers.
PHA 6148C-Pharmaceutical Product Formulation (3) The
rationale and design of pharmaceutical dosage forms, partic-
ularly from a chemical and biopharmaceutical viewpoint.
PHA 6155-Hospital Pharmacy Seminar (1) Required of hos-
pital pharmacy residents, but not more than two credits are
allowed. Oral reports related to hospital pharmacy. Discus-
sion of problems.
PHA 6225-Hospital Pharmacy Administration (2) Develop-
ment, functions, responsibilities, organization, and adminis-
tration of the hospital and the hospital pharmacy depart-
ment. Viewpoint of administrative responsibilities of the
hospital pharmacist.
PHA 6235-Advanced Pharmaceutical Law (3) Study of the
Federal Food, Drug and Cosmetic Act and various state and
local laws applicable to drug manufacturers, wholesalers,