tion of concepts of immunopathology and immunogenetics to
 the clinical laboratory management of immunologic problems.
 Students specializing in clinical immunology must spend three
 consecutive semesters in this rotation.
 Clinical Virology
 BMS 6618C-Clinical Virology: A Rotation (2-12; max: 12)
 Prereq: consent of instructor. Participation in all phases of prac-
 tical clinical virology. Laboratory training in methodology,
 clinical interpretation and significance of clinical virology, with
 emphasis on diagnostic procedures. Individual investigative
 projects. Students specializing in clinical virology must spend
 three consecutive semesters on this rotation.

 PHARMACOLOGY AND
 THERAPEUTICS
 College of Medicine
 GRADUATE FACULTY 1982-83
 Chairman: A. H. Neims. Graduate Coordinator: S. Baker.
 Graduate Research Professor: T. H. Maren. Professors:
 M. J. Greenberg; K. C. Leibman; A. H. Neims; D. N.
 Silverman. Associate Professors: G. M. Carlson; L. C.
 Garg; K; Kadzielawa; W. R. Kem; E. Meyer; T. F. Muther;
 J. B. Pritchard. Assistant Professors: S. Baker; S. Childers;
 W. E. Ross; K. T. Shiverick:
 The Department of Pharmacology and Therapeutics
 offers a program leading to the degree of Doctor of
 Philosophy in the medical sciences with specialization
 in pharmacology.
 The general research focus of the department is mech-
 anistic, at the cellular and molecular levels. Specific areas
 of research include receptor and membrane pharmacol-
 ogy; autonomic, renal, developmental, endocrine, gas-
 trointestinal, and neuropharmacology; teratology; fluid
 secretion and carbonic anhydrase inhibition; cancer
 chemotherapy and carcinogenesis; physical chemistry of
 enzymes; opioid peptides, drug metabolism; and envi-
 ronment and marine toxicology.
 Applicants should present undergraduate course
 credits in chemistry, including quantitative analytical,
 organic, and physical chemistry; elementary physics and
 biology; and mathematics through calculus. Otherwise
 well-qualified students with certain deficiencies in
 preparation will be allowed to make these up during the
 first year of graduate study. In addition to elementary and
 advanced study in pharmacology, candidates will pur-
 sue courses in biochemistry, physiology, and other
 medical sciences as determined by consultation with
 their advisory committees.
 BMS 5465-Advanced Medical Pharmacology (4)
 BMS 6400-Introduction to Pharmacology (5) Prereq: elemen-
 tary courses in biochemistry and physiology. Overview of the
 entire field of pharmacology as the study of the interactions be-
 tween living systems and foreign chemicals. Intended to prepare
 majors for advanced courses or to familiarize nonmajors with
 the area.
 BMS 6420-Seminar in Pharmacology (1) Prereq: BMS 6400.
 Research reports and discussions of current research literature.
 by graduate students, faculty, and invited lecturers.
 BMS 6463-Molecular Pharmacology (5) Prereq: BMS 6400,
 CHM 3401..A biochemical approach to the actions of drugs,
 stressing analysis of drug-receptor interactions, structure-activity
 relationships, kinetics of distribution of drugs, and metabolism
of foreign compounds.
BMS 6466-Physiological Pharmacology (5) Prereq: BMS 6400.
Influence of drugs upon physiological systems, including
nervous, endocrine, cardiovascular, renal, gastrointestinal, and
musculoskeletal.
BMS 7421-Research Methods in Pharmacology (1-3; max: 6)
Readings, discussions, and practical experience with modern


 PHARMACOLOGY AND THERAPEUTICS / 117

 methods used in pharmacology. Chemical and biological
 methods.
 BMS 7423-Topics in Pharmacology (1-3; max: 12) Seminars,
 informal conferences, or laboratory work on selected topics in
 pharmacology.
 BMS 7467-Physiology and Pharmacology of Excitable Mem-
 branes (2) Membrane ionic permeability changes underlying
 action and synaptic potential generation described in detail. Ap-
 plications of electrophysiological and radioactive tracer tech-
 niques to analysis of drug action on excitable membranes.


 PHARMACY
 College of Pharmacy
 GRADUATE FACULTY 1982-83
 Chairman: M. A. Schwartz. Graduate Coordinator: R. J.
 Bergeron. Graduate Research Professor: E. R. Garrett.
 Professors: O. E. Araujo; S. J. Curry; K. F. Finger; J. H.
 Perrin; S. G. Schulman; M. A. Schwartz; R. B. Stewart;
 F. A. Vilallonga. Associate Professors: R. A. Angorn; P. L.
 Doering; F. P. Field; L. S. Hendeles; C. L. Kimberlin;
 M. A. Lemberger; W. C. McCormick; M. W. McKenzie;
 M. P. Pevonka; R. L. Yost. Assistant Professors: D.
 Bradham; C. L. DeVane; V. P. Gotz; M. J. Katovich; L. M.
 Lopez; J. A. Pieper; J. D. Robinson; J. W. Simpkins; M.
 Theodorakis.
 The College of Pharmacy offers the Doctor of Philos-
 ophy and the Master of Science in Pharmacy degrees
 with a major in pharmaceutical sciences. The approved
 areas of specialization within the major of pharmaceutical
 sciences are medicinal chemistry and pharmacy. The
 specialization of pharmacy allows students to concen-
 trate their study in the. following areas: pharmaceutics,
 pharmaceutical biology, pharmacy health care admin-
 istration, and hospital pharmacy administration.
 -Students who wish to concentrate their study in the!
 area of pharmacy health care administration must have
 a baccalaureate degree but applicants do not need an
 undergraduate degree in pharmacy. Students who wish
 to concentrate their study in the area of hospital
 pharmacy administration must have a Bachelor of
 Science in Pharmacy and licensure as a pharmacist, while
 an undergraduate degree in pharmacy, chemistry, biol-
 ogy, or related sciences will be accepted in the scien-
 tific areas.
 HCA 5455-Quality Assurance in the Health System (2) Prereq:
 HCA 6101 or consent of instructor. Various factors relating to
 quality assurance issues are examined. Past and current pro-
 grams are critically reviewed, while developing the guidelines,
 processes, etc., for initiating and maintaining new approaches.
 HCA 6117-Health Policy Analysis (3) Prereq: STA 6201, 6707
 or equivalent and ECP 6536. Application of, research
 methodologies which involve economic analysis to specific
 health policy issues. Computerized data sets of social, economic,
 and health services utilization characteristics are provided.
 HCA 6425-Health Care Administration in Long Term Care
 Settings (2) Prereq: HCA 6101 or consent of the instructor.
 Disease and health care utilization trends of the elderly popula-
 tion are reviewed. The organizational structure of LTC facilities
 is examined. The regulation, reimbursement, and quality
 assurance mechanisms used in LTC are analyzed.
 PHA 5121-Clinical Pharmacokinetics (3) Prereq: PHA 4120
 or by special arrangement. Integrating and applying pharmaco-
 kinetic principles to formulate a rational dosage regimen con-
 sidering various patient factors and drug product factors.
 PHA 5126-Surface Chemistry of Biological Systems (2) Study
 of surface chemistry of fluid interfaces and its application to
 biomembranes and drug-biomolecule interactions.
 PHA 5356-Cancer Chemotherapy (2) Prereq: PHA 4350 and
 BCH 4203. Coreq: PHA 4436. The chemotherapeutic agents
which are currently in clinical use or under trial are classified