130 Y. Yuthavong Philippines, formally established in 1960, is an early example of success of such international cooperation, giving to the world the IR8 and a host of semi-dwarf rices which now account significantly for the present high world productivity in rice. Other institutions established later, including the International Maize and Wheat Improvement Center (CIMMYT) in Mexico, the International Laboratory for Research on Animal Diseases (ILRAD) in Kenya, together with the IRRI, are now supported by the Consultative Group on International Agricultural Research (CGIAR), in turn sponsored by the Food and Agriculture Organization (FAO), the World Bank, UN Development Programme (UNDP), various governments and funding agencies. The CGIAR is often cited as a successful model of international cooperation in research and training for a specific mission, i.e., to increase food production in the developing world. Another example of global cooperation for a specific mission, to which biotechnology is making a significant contribution, is the UNDP/World Bank/World Health Organization (WHO) Special Programme for Research and Training in Tropical Diseases. Started in the mid-seventies, the Special Programme aims at the alleviation of six major tropical diseases mainly predominant in the developing world. The major tropical diseases are also the main con- cern of other non-governmental organizations, e.g., the Rockefeller Foun- dation Programme on Great Neglected Diseases of Mankind. A number of new drugs and vaccines are being developed through these programmes. A few efforts on the international scale have focused on biotechnology as the major tool towards development of the Third World countries. The effort by UNIDO to set up the International Center for Genetic Engineer- ing and Biotechnology (ICGEB) is the most extensive one with original participation from both developing and some developed countries, al- though it has unfortunately suffered from the disinterest of the major countries. These problems are partly due to the expectations and fears concerning international transfer and development of this powerful tech- nology, much of which is proprietary and involves major trade and indus- trial interests. Nevertheless, the establishment of ICGEB has sensitized many developing countries to the potential benefits of biotechnology, and the Center itself, with the two components in Trieste (Italy) and New Delhi (India), may yet make significant impact on the developing coun- tries, depending on acquisition of a high calibre staff and a well-chosen programme of activity. An appraisal of the UNIDO effort to set up the ICGEB has been recently given (Zimmerman, 1984 a,b). Other efforts in international cooperation on biotechnology for the ben- efit of developing countries include the agreement between the United Nations University and Venezuela to set up the International Institute for