Impacts of Biotechnology on Marine and Environmental Sciences Rita R. Colwell Department of Microbiology University of Maryland College Park, Maryland Dramatic changes are taking place in oceanography and marine sci- ences, and the economic value of research underway in applying biotech- nology to these fields should not be understated. Shellfish harvests repre- sent income of millions of dollars each year for coastal states, including Florida, California, Texas, and Maryland. Worldwide, notably in Asian countries, the fisheries industries represent $300 to $400 million each year in production of seafood and marine products. The state of Maryland has a special interest in marine biotechnology because of its major natural re- source, the Chesapeake Bay. Landed harvests of Chesapeake Bay fisheries can be estimated at about $13 million, and significantly more, if one takes into account all of the auxiliary activities on the Chesapeake Bay and their value to the state. The economic value, therefore, approaches the billion dollar a year range. Thus, fisheries, as an industry, is significant on an economic basis, even without considering fish as a source of protein for millions of people each year. A few examples of the value of marine biotechnology in enhancing fish- eries' production and the maritime industries will be discussed in this pa- per. Excellent examples of the potential of marine biotechnology applied to the shellfish industry include the work of Dr. Daniel Morse and his colleagues at Santa Barbara, and the oyster studies underway at the Uni- versity of Maryland. In these cases, genomic libraries for the abalone and oyster, respectively, have been established. In addition to genetic engineering of shellfish, a great deal of work is being done on fish. Although the latter is not covered in detail here, it must be pointed out that genetic engineering of fish represents a very active area of research. Japanese scientists have reported successful cloning of the growth hormone in salmon. Scientists working in California have also re- ported, independently, the cloning of the salmon growth hormone. At Johns Hopkins University and the University of Maryland, a team of scien- tists have cloned the growth hormone in trout. A group of scientists in Vancouver, Canada, demonstrated the use of growth hormone to obtain