ARTICLE I The Contracting Parties hereby acknowledge the regime of permanent neutrality for the Canal established in the Treaty Concerning the Permanent Neutrality and operation of the Panama Canal and associate. themselves with its objectives. ARTICLE 11 The Contracting Parties agree to observe and respect the regime of permanent neutrality of the Canal in time of war as in time of peace, and to en' sure that vessels of their registry strictly observe the applicable rules. ARTICLE III This Protocol shall be open to accession by all states of the world, and shall enter into force for each State at the time of deposit of its instrument of accession with the Secretary General of the Organization of American States. TIAS 10029