104
110
180 
90
S80
0
a 70
V
S60
o 0 U 40 0. 30
20 10
0 -I I I
0 20 40 60 80 100 120 Time(Hours)
Figure 43. Non specific degradation of the G90D target. The sum of the substrate and product at each time point allows the determination of the non-specific degradation during a time-course of the cleavage of substrate by G90D 1.