4
the major causes of fatigue (29). If this is the case,
respiratory acidosis should reduce the developed tension
of a twitch contraction.
In the final chapter of this dissertation, a brief
discussion of the possible theories for the mechanism of
fatigue observed in these experiments is presented. It
is evident that further research will be necessary to
permit evaluation of these theories with respect to
fatigue of the canine gastrocnemius-plantaris muscle
group. However, considerable evidence has accumulated
as a result of my studies, which disputes several of the
current theories of fatigue.