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EFFECTS OF RESPIRATORY ACIDOSIS ON THE TWITCH
CONTRACTION 6 8
Introduction 68
Methods 69
Results 70
Discussion 79
SUMMARY 89
O2 Uptake and Developed Tension 89
Time-Course of the Twitch Contraction in
Fatigue 90
Acidosis and the Twitch Contraction 91
PROPOSED HYPOTHESES FOR SKELETAL MUSCLE FATIGUE . 92
Depletion of Calcium at Lateral Sacs 92
Compartmentalization of Calcium Within the
Lateral Sacs 93
Attenuated Trigger for Release of Calcium ... 93
Reduced Binding Sensitivity for Calcium .... 94
CONCLUSIONS 9 5
APPENDIX 9 6
BIBLIOGRAPHY 100
BIOGRAPHICAL SKETCH 106
IV